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| Bivalirudin |
| Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin.1,3,5 It inhibits both circulating and clot-bound thrombin5>, while also inhibiting thrombin-mediated platelet activation and aggregation6. Bivalirudin has a quick onset of action and a short half-life.1 It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS).1 It does not require a binding cofactor such as antithrombin and does not activate platelets.3,4 These characteristics make bivalirudin an ideal alternative to heparin. Manus Aktteva offers Bivalirudin, 128270-60-0, for RND and its crude form for your evaluation requirements with supportive technical package required for evaluation.
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| Product Reference ID: MA-GA-551-O |
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| Chemical Name: |
D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
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| Description |
| CAS number |
128270-60-0 |
| Synonym |
Bivalirudin, (15S,21S,24S,27S,30S) - 15 - (2-amino-2-oxoethyl) - 1 - [(2S)-1-{(2S)-2-[({(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidin-2-yl} carbonyl)amino]-5-carbamimidamidopentanoyl}pyrrolidin-2-yl] - 24 - benzyl-30-({(2S,3S)-1-[(2S)-2 -{[(2S)-4-carboxy - 1 - {[(2S)-4-carboxy-1-{[(2S)-1-{[(1S)-1-carboxy-3-methylbutyl]amino}-3 -(4-hydroxyphenyl) - 1 - oxopropan-2-yl]amino} - 1 - oxobutan-2-yl]amino}-1-oxobutan-2-yl]carbamoyl}pyrroli\ndin -1-yl]-3-methyl - 1 - oxopentan-2-yl}carbamoyl) - 27 - (2-carboxyethyl) - 21 - (carboxymethyl) - 1,4,7,10,13,16,19,22, 25,28 - decaoxo -2,5,8,11,14,17,20,23,26,29 -decaazatritriacontan-33-oic acid |
| Molecular Formula |
C98H138N24O33 |
| Molecular Weight |
2180.29 |
| Specifications |
Purity(HPLC)=99%; White or almost white powder |
| Packing |
Export worthy packing |
Material Safety Data Sheet
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Available on request
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| Availability |
RND & Evaluation |
| Drug Master File |
Can be made available |
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Are you looking for Bivalirudin Intermediates ? Please click here to browse through the list of Bivalirudin Intermediates available with us. |
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| Bivalirudin, 128270-60-0, GMP, DMF, suppliers, manufacturers, India, China, Drug Master File |
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NOTE:
- Manus Aktteva, India is successfully representing suppliers, manufacturers from INDIA, suppliers, manufacturers from CHINA, and fulfilling the requirements of buyers from EUROPE, USA, South America, Japan, Korea, Taiwan, Australia, & middle-east.
Keywords: New Molecules, patents, R&D, cas, cas number, product, supplier, suppliers, vendor, vendors, price, prices, api, apis, active pharmaceutical ingredient, ingredients, importer, exporter, distributor, import, export, sale, producer, manufacturer, synthesizer, synthesis, gmp, cgmp, fda, dmf, cgmp, cos, inventory, stock, prompt shipment, compounding, compound, research, development, patent, r and d, pharma
- Please note that products falling in to controlled substance category shall be exported directly from the manufacturer principals only against receipt of original import permission issued by concerned authorities of the importing country.
Product enquiries may please be sent to info@manusaktteva.in, udeetjbanker@gmail.com, jdbanker@gmail.com
PATENTS:
- => Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer's risk.
=> Products currently covered by valid US Patents are offered for R&D use in accordance with 35 USC 271 +A13(1)
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